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  <description>The latest developments in HIV prevention (PrEP &amp; PEP): new medications, guideline changes, approvals and access news — medically reviewed and plainly explained.</description>
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    <title>New tools: drug-interaction checker now covers 112 medicines</title>
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    <pubDate>Wed, 15 Jul 2026 09:00:00 GMT</pubDate>
    <category>Guidance</category>
    <description>Our free PrEP drug-interaction checker now spans 112 medicines, supplements and recreational drugs — each showing whether it's safe, needs monitoring, or is prohibited with Truvada, Descovy and Apretude, with the mechanism explained.</description>
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    <title>Twice-a-year PrEP: FDA approves lenacapavir (Yeztugo)</title>
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    <pubDate>Fri, 20 Jun 2025 09:00:00 GMT</pubDate>
    <category>Approval</category>
    <description>Lenacapavir, a long-acting capsid inhibitor given as an injection just twice a year, was approved by the FDA in 2025 for HIV pre-exposure prophylaxis — the longest-acting PrEP yet, with near-100% protection in the PURPOSE trials.</description>
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    <title>WHO recommends lenacapavir for PrEP worldwide</title>
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    <pubDate>Mon, 14 Jul 2025 09:00:00 GMT</pubDate>
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    <description>The World Health Organization recommended twice-yearly lenacapavir as an additional PrEP option, urging countries to roll it out — a major step for global access to long-acting HIV prevention.</description>
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    <title>CDC issues Doxy-PEP guidelines to cut STIs</title>
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    <pubDate>Wed, 05 Jun 2024 09:00:00 GMT</pubDate>
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    <description>The CDC published guidance on Doxy-PEP — a single 200 mg dose of doxycycline within 72 hours after sex to lower the risk of bacterial STIs for gay/bisexual men and transgender women.</description>
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    <title>USPSTF "Grade A" — PrEP must be covered with no cost-sharing (US)</title>
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    <pubDate>Tue, 22 Aug 2023 09:00:00 GMT</pubDate>
    <category>Access</category>
    <description>The US Preventive Services Task Force gave PrEP its top "A" rating, meaning most insurers and Medicaid must cover the medication and its follow-up visits and labs with no out-of-pocket cost.</description>
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    <title>Apretude (cabotegravir): the first injectable PrEP</title>
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    <pubDate>Mon, 20 Dec 2021 09:00:00 GMT</pubDate>
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    <description>Apretude became the first long-acting injectable PrEP — an injection every 2 months instead of a daily pill — approved for all populations at risk, including cisgender women.</description>
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